Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity.

نویسندگان

  • Dokyoung Kim
  • Sunderraman Sambasivan
  • Hyoseok Nam
  • Ki Hean Kim
  • Jin Yong Kim
  • Taiha Joo
  • Kyung-Ha Lee
  • Kyong-Tai Kim
  • Kyo Han Ahn
چکیده

Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.

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عنوان ژورنال:
  • Chemical communications

دوره 48 54  شماره 

صفحات  -

تاریخ انتشار 2012